Medires Publishers - Article

Abstract

Silybum marianum   belongs  to family Asteraceae. Also, kn   as milk thistle, blessed   thistle, mediterranian   milk thistle. Onopordum   acanthium or Cirsium vulgare is also known as Scotch Thistle. Purple flowers, dull   green   leaves. 200 cm long.It   is   native to Mediterranean region. Found in warm   wetland places. Not   found  in dry   areas. It   develops in soil pH 5.5-7.5. Can germinate in 3-4 or C.NPK Ratio 50:30:60. Phytochemical  is flavonolignan silymarin.

Traditional milk thistle extract is made from the seeds, which contain approximately 4–6% silymarin.[22] The extract consists of about 65–80% silymarin (Silybin  A ,B ,Isosilybin  A,B , Silydianin ,Isosilychristin  ,silychristin ,flavonoid -  taxifolin, silibinin , 

Silymarin –silybin A & silybin B (diastereoisomers), polyphenolic   molecules.

(a flavonolignan complex) and 20–35% fatty acids, 

Silymarin  seed   extract has     potent anticancer effects.  02.5 gm  powder  given daily  in  10 ml aqueous   solution  is effective  against   cancer.

But   in sm   persons  it causes   upset   stomach  & allergy. (25). Also, they  hv   mycotoxin conc 38mg/kg.

When  cattle  eat   KNO3  it  breaks   into nitrite  , which   combine  hemoglobin  to  form methemoglobin  &  block  O2   transport .

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