Case Report | DOI: https://doi.org/10.58489/2836-2322/004
Dr. Eng., Lecturer NationalAcademy of Sciences- Sofia, Bolgaria.
Correspondng Author: Vasil Lyubenov Kanisov
Citation: Kanisov V.L, (2022). Quantum Method of Pharmacological studies of Biologically active substances (bav) of Medicinal plants with Antiviral and Endothelioprotective Properties. Pharmacy and Drug Development. 1(1). DOI: 10.58489/2836-2322/004
Copyright: © 2022 Vasil Lyubenov Kanisov, this is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received Date: 2022-07-23, Received Date: 2022-07-23, Published Date: 2022-08-15
Abstract Keywords: medicinal plant, yellow color, quantum technique, medical characteristic
Abstract
In this work, a comprehensive study of all medicinal plants with the yellow color of flowers is carried out. This morphologically valuable feature is color, associated with electromagnetic radiation (absorption), as the main factor in the formation of secondarymetabolites (BAV). As a resultof comparative analysisand quantum researchmethodology, we identified plant species that have a characteristic therapeutic characteristic - antiviral and have endothelioprotective properties.
Introduction
The specific characteristics of the metabolism of various plant species have determined their selective ability to accumulate chemicalsthat have high physiological activity at low concentrations - the so-called Biologically active substances (BAS). The physiological activity of substances can be considered both from the point of view of the possibility of their pharmacological study and medical use [1] , and from the point of view of maintaining the normal functioning of the human body [2] or giving a group of organisms special properties [3]. For example, flavicin (natural flavonoids) possessing endothelialprotective properties [4].
Secondary metabolites are the most important physiologically active compounds in the plant world. Their number, investigated by pharmacological science, is increasing every year. At the moment, only about 15% of all plant species have been studied for the presence of these substances.
Compounds of secondary metabolism, unlike primary metabolites, have functional significance not only at the level of the cell, but at the level of the tissue and cell of the whole plant. Most often, these substances perform "ecological" functions, i.e., protect the plant from various pests and pathogens, participate in the reproduction of plants, giving color and smell to flowers. and fruits, provide interaction of plants with each other and with other organisms in the ecosystem.
In this particular case, we consider flavonoids as compounds of secondary metabolism in the plant. The natural functions of flavonoids are poorly understood. It was assumed that due to the ability to absorb ultraviolet radiation (330-350 nm) and part of the visible light (520-560 nm), they protect plant tissues from excess radiation. In mammals, flavonoids are able to change the activity of many metabolic enzymes [5].
It has been established that in the irus SARS-CoV-2 is sensitive to ultraviolet irradiation with a dose of at least 25 mJ / cm2 [6] In this range, absorption of ultraviolet light by a medicinal plant with yellow light is observed.
Numerous studies on the study of angioprotective and antioxidant properties of natural flavonoids, including diabetic micro- and microangiopathy, have revealed that flavonoids are among the promising groups with endothelialprotective effects. [7].
The aim of our study was to study the effect of flower color as specific characteristics of the metabolism of different plant species, which determined their ability to accumulate the chemicalM, the main flavonoid. Which flavonoids, in turn, have specific pharmacological properties.
Materials And Methods
The object of the study was any medicinal plants with a yellow color of flowers, as well as yellow - yellow, with the addition of a different color. Yellow - colors of electromagnetic radiation with wavelengths from 550 to 590 nm [8]
We take electromagnetic radiation (absorption) as the main factor in the formation of secondary metabolites, to which we apply the Quantum Research Methodology.
According to the special theory of relativity (SRT), there is a connection between mass and energy, expressed by Einstein's famous formula:
{\displaystyle E=mc^{2},} (1)
Where: {\displaystyle E} is the energy of the system; {\displaystyle m} is its mass; {\displaystyle c} is the speed of light in a vacuum.
In a vacuum, the energy and momentum of a photon depend only on its frequency ( {\displaystyle \nu } equivalent, on the wavelength {\displaystyle \lambda =c/\nu }):
(2)
Where: - Photon (light) energy; - Planck's constant (6.624. 10-34 j.s); - Wave frequencies
I consider the mass () of a photon (officially, a term that goes out of use in quantum physics) to be equal to:
(3) See: Table 1 [9]
The pressure of electromagnetic radiation, the pressure of light () is the pressure exerted by light (and in general electromagnetic) radiation incident on the surface of a body. [9]
The pressure of electromagnetic radiation [10] is a consequence of the fact that it, like any material object with energy and moving at speed, also has a momentum: .
And since for electromagnetic radiation,
Experimentally, light pressure was first studied by P. N. Lebedev in 1899. In electrodynamics, the pressure of electromagnetic radiation is described Results And Discussion
According to the formula (1), (2) and (3), we will compile Table 1. From Table 1 - row "Color" "Yellow" we will make Table 2.
Table 1 - Correspondences of lengths, frequencies, mass and energy of electromagnetic radiation and colors.
Color | Wavelength range (λ), [nm] | Wave frequency range(ν), [Hz]1. 1014 | Range Mass of photons (m) [kg]1. 10-36
| Photon energy range (E) [eV] |
Infrared
| 770 - 40 000 | < 3> | 2,206 - 0,3577 | < 1> |
Red
| 625- 740 | 4,05-4,8 | 3,52 - 2,99 | 1,68 - 1,98 |
Orange
| 590 -625 | 4,8-5,1 | 3,74-3,52 | 1,98 - 2,10 |
Yellow
| 565 – 590 | 5,1-5,3 | 3,89-3,74 | 2,10 - 2,19 |
Green
| 500 – 565 | 5,3-6,0 | 4,14-3,89 | 2,19 - 2,48 |
Blue
| 485 – 500 | 6,0-6,2 | 4,56-4,14 | 2,48 - 2,56 |
Blue
| 440 – 485 | 6,2-6,8 | 5,01-4,56 | 2,56 - 2,82 |
Violet
| 380 – 440 | 6,8-7,9 | 5,81-5,01 | 2,82 - 3,26 |
Ultraviolet | 0,1- 400 | 2,998.104- 7,50 | 22 071,1 – 5,511 | 12 398–3,1 |
Table 2 - A complete list of plants with yellow flower flowers
Latin | Name | Latin | Name |
1. Achillea clypeolata S.S. | Yarrow yellow shield-shaped) | 60. Jasminum fruticans L. | Jasmine shrub |
2. Adonis vernalis L. | Adonis spring | 61. Kickxia spuria (L.) Dum. | Kixia real |
3. Agrimonia eupatoria L. |
| 62. Lactuca serriola L. | Compass lettuce |
4. Ajuga chamaepitys (L.) Schreb. | Tenacious elut | 63. Lathyrus pratensis L. | Meadow chin |
5. Anemone ranunculoides L. | Buttercup windmill | 64. Lepidium perfoliatum L. | Pierced bedbug |
6. Anethum graveolens L. | Garden dill | 65. Linaria vulgaris Mill. | Common flaxseed |
7. Anthemis tinctoria L. | Pupavka dye | 66. Lotus corniculatus L. | Lyadvenets horned |
8. Anthyllis would violate L. | Common ulcer | 67. Melilotus officinalis (L.) Pall.
| Donnik officinalis |
9. Aristolochia clematitis L. | Kirkazon | 68. Oenothera biennis L. | Biennial donkey |
10. Artemisia absinthium L. | Wormwood | 69. Parsnip sativa L. | Parsnip |
11. Asparagus officinalis L.* | Pharmacy asparagus | 70. Potentilla anserina L. | Goose lapchatka |
12. Astragalus glycyphyllos L. | Astragalus sweet-leaved | 71. Potentilla erecta L. | Lapchatka erecta |
13. Barbarea vulgaris R. Br. | Common meadowsweet | 72. Potentilla reptans L. | Creeping lapchata |
14. Berberis vulgaris L. | Common barberry | 73. Prangos ferulacea (L.) Lindl. | Prangos
|
15. Bidens tripartite L. | Three-part series | 74. Primula etalior Hill. | Primrose tall |
16. Brassica (Sinapis) nigra Koch
| Black mustard | 75. Primula vulgaris Huds. (P. acaulis Jacq.) | Common primrose |
17. Brassica juncea (L.) Czern. et Coss. | Sarepta mustard | 76. Primula veris L. (P. officinalis Jacq.) | Spring primrose |
18. Bryonia alba L. | Step white | 77. Pulicaria vulgaris Gaertn. | Bloshnica |
19. Bupleurum rotundifolium L. | Round-leaved volodushka | 78. Radiola rosea L. | Radiola pink |
20. Caltha palustris L. | Swamp koluzhnitsa | 79. Ranunculus acris L. | Buttercup caustic |
21. Carthamus lanatus L. | Woolly Safflower | 80. Ranunculus repens L. | Creeping buttercup |
22. Cerinthe minor L. | Small waxer | 81. Ranunculus would be L. (It would be verna Huds.) | Chistyak |
23. Chelidonium majus L. | Celandine large, warthog | 82. Reseda luteola L. | Reseda dye, cerva |
24. Chrisosplenium alternifollum L. | Common spleen | 83. Reseda lutea L. | Reseda yellow |
25. Cnicus benedictus L. | Cnikus blessed | 84. Rhinanthus minor L. | Small rattle |
26. Colutea arborescens L. | Tree bladderwort | 85. Rorippa pyrenaica (L.) Rchb. | Zherushnik Pyrenees |
27. Cornu’s mas L. | Common dogwood | 86. Rubia tinctorum L. | Madder dye |
28. Cotinus purpose coggygria. | Leather mackerel | 87. Graveolens route L. | Fragrant rue |
29. Descurainia sofia (L.) Webb. | Discurainiia of Sofia | 88. Salix alba L. | White willow, vetla, whitewash |
30. Digitalis grandiflora Mill. | Large-flowered bridge | 89. Salix fragilis L. | Willow brittle |
31. Digitalis lanata Ehrh. | Woolly obere | 90. Sambucus racemosa L. | Elderberry tassel |
32. Doronicum columnae Ten. | Doronicum | 91. Scabiosa columbaria L. | Scabiosa pigeon |
33. Erysimum diffusium Ehrh. | Jaundice spreading
| 92. Sedum acre L. | Ochitok caustic |
34. Erysimum crepidifolium Rchb. | Jaundice toothed | 93. Sedum maximum Suter | Big spruce, hare cabbage |
35. Erysimum repandum L.
| Jaundice notched-toothed
| 94. Senecio nemorensis L. | Oak crossbill |
36. Euphorbia cyparissias L. | Milkweed cypress | 95. Senecio jacobaea L. | Jacob's Cross |
37. Filago arvensis L. | Field toad | 96. Senecio vulgaris L. | Common crossbill |
38. Filago vulgaris Lam. | Small toad | 97. Sempervivum ruthenicum Schn. | Molodilo Russkoe |
39. Foeniculum vulgare Mill. | Fennel vulgaris | 98. Sideritis montana L. | Zheleznitsa gornaya |
40. Galium verum L. | Real underbrush | 99. Sideritis scardica Grsb. | Railway |
41. Galium cruciatum Purpose. | Cruciform underbrush | 100. Silena otites (L.) Wibel. | Smolevka long-eared |
42. Genista tinctoria L. | Woodwax | 101. Sisymbrium officinale (L.) Purpose. | Gulyavnik officinalis |
43. Genista segittalis L. | Drock lancet | 102. Solidago virgaurea L. | Common goldenrod |
44. Gentiana lutea L. | Gentian yellow | 103. Stachys straight L. | Chisel Straight |
45. The dotted gentian L. | Pinpoint gentian | 104. Stachys annua L. | Annual cleaner |
46. Geum montanum L. | Mountain gravilate | 105. Tanacetum vulgare L. | Feverfew maiden, golden-flower maiden |
47. Geum urbanum L. | Urban Gravilate | 106. Taraxacum officinale Webber | Pharmacy dandelion |
48. Glaucium flavum Cr. | Glaucium yellow | 107. Telekia speciosa Bmg. | Telekia the Beautiful |
49. Gnaphalium uliginosum L. | Sushenitsa topyana | 108. Tilia grandifolia Ehrh. | Linden heart-leaf |
50. Helychrisum arenarium Moench | Sandy cumin | 109. Tilia parvifolia Ehrh. | Small-leaved linden |
51. Heracleum sibiricum L. | Hogweed | 110. Tilia tomentosa Moench | Lime pushy, lime voylocha |
52. Hieracium pilosella L. | Hairy hawk | 111. Thalictrum minus L. | Basilisk minor |
53. Hyoscyamus niger L. | Black belena | 112. Tragopogon pratensis L. | Meadow goat |
54. Hypericum perforatum L. | St. John's wort perforated | 113. Tribulus terrestris L. | Tribulus creeping |
55. Hypochaeris maculata L. | Speckled grouse | 114.Tussilago farfara L. | Coltsfoot |
56. Inula germanica L. | Elecampane Germanic | 115. Verbascum phlomoides L. | Woolly mullein |
57. Inula britannica L. | Elecampane British | 116. Verbascum thapsiforme Schrad. | Tupsoid mullein, tall mullein |
58. Inula helenium L. | Elecampane high | 117. Veratrum album L.* | Chemerica white |
59. Iris pseudacorus L* | Yellow killer whale | 118. Viscum album L. | White mistletoe |
Findings
1. Biologically active substances (BAV) of all medicinal plants Table 2, have high pharmacological antiviral, bactericidal, anti-inflammatory, antiseptic and insecticidal activity.
2. Looking at the equations (4), (5), (6), and (7) it turned out that the plants emitted yellow color of the flowers (in the energy range: 2.10 - 2.19 eV) absorb infrared light (in the energy range: < 1>), which light possesses some properties like: increasing the diameter of the vessels and improving blood circulation (improving endothelial function); activation of cellular immunity (antiviral activity) ; removal of tissue swelling and inflammation (improvement of endothelial function); relief of pain syndromes; improvement of metabolism; removal of emotional stress; restoration of water-salt balance; normalization of hormonal levels.
3. Quantum mechanisms and biological structures are related – their properties are uniform and/or supplemented. This connection can be established by creating a mathematical-physical-biological model, and in the future by studying their pharmacodynamic and pharmacokinetic properties, and behavior, through this model
Summary
In this work,a comprehensive study of all medicinal plantswith yellow flowersis carried out. This morphologically valuable feature is color, associated with electromagnetic radiation (absorption), as the main factor in the formation of secondary metabolites. As a result of comparative analysis and quantum research methods, we have identified plant species that have the same therapeutic characteristics.
References